1. Alpha GPC is a choline source synthesized from sunflower or soy. So that's where the idea came from, i need a little bit of external help. A big list of neurofeedback studies (adhd, depression, performance enhancement) | Looking for neurofeedback reports I wanted to investigate whether a local health clinic offering neurofeedback with neuroptimal device was legit and whether this neuroptimal device is capable of doing serious neurofeedback or if it's watered down bs, so I went to see what kind of studies were there. The first similarity between these two is that they are both nootropics. Alpha-GPC didn't make me alert so much as unable to fall asleep. Thus, alpha GPC is often used … The only bad thing i can note is that my strive to be more productive adds to my eye strain, in the long run since i work a lot with a computer, New comments cannot be posted and votes cannot be cast. Piracetam … Alpha GPC. Press question mark to learn the rest of the keyboard shortcuts. In combination with other nootropics, it works as a potentiator boosting cognitive capabilities. Alpha-GPC is a natural choline compound. This is yet another reason why more regimented testing is required when you try a new supplement. Your panic was doubled by the fact that you didn't quite understand what was going on and that could have been easily avoided. This has happened to me twice before but to a lesser degree, and it only lasted 2 days. Discussion of nootropics and cognitive enhancers. Ended up quitting it because the price was high compared to CDP choline and I couldn't tell the difference. Alpha-GPC has two distinct but very different effects. It's just me too but I've noticed it with CDP choline on its own. I wanted to alert people to the possibility that AGPC CAN cause these effects. I get really sore and tired body load towards the end of the day after a combo of alpha-gpc and aniracetam. Press question mark to learn the rest of the keyboard shortcuts. It works on its own as a powerful memory booster. Alpha GPC naturally occurs in your brain as a byproduct of phosphatidylcholine (PC). Cookies help us deliver our Services. I never noticed anything when I started, but I thought it would be a good idea to keep taking it. Page 1 of 2 - Alpha GPC experience - posted in Brain Health: I have been taking Alpha GPC for a little over a month now. Piracetam. L-Alpha Glycerylphosphorylcholine (Alpha GPC) The Alpha GPC form of choline is one of the most potent. I wonder why that is. It was better than Modafinil. Then I add 1 or 2 capsules of Alpha-GPC which usually adds to be 150-300mg’s. To my surprise 30 minutes after taking it my mood lifts and I feel incredibly focused and motivated, I spent a few hours doing some math lessons online and loved it. Caffeine pills. You only get one brain! Alpha gpc and uridine are my fav mood enhancers. I used to take it all the time, 300mg twice a day with some good results. Any choline makes me sad and depressed, except for eggs. For those prone to depression, it is not a fun experience. By weight, alpha GPC is considered the best acetylcholine precursor and can help mitigate age related degenerative diseases similar to citicoline. You can most certainly use other choline sources out there or just have a diet rich in choline but I personally like Alpha GPC the most. On its own it can really improve my workouts and motivation outside the gym. Because it doesn’t have to cannibalize its own cells to get more choline. It is not atypical by any sense of the word. It is worth to mention that i have a strong analytical mind and strong cognitive abilities. What is Alpha GPC. Sometimes it gives fatigue/inflammation/depression. After another hour, the feeling slightly diminished, and left me with a lighter but strong feeling of concentration. It works so well that it’s prescribed throughout Europe for memory loss (it’s over-the-counter in the U.S.). Our bodies seem to respond the same way to these two choline supplements as they do to dietary sources of choline. My work requires a lot of that. Alpha GPC (choline) is a miracle for my ADHD and mood. Sorry to hear about the ordeal, that sounds god-damned awful. From this increased acetylcholine synthesis, the benefits above are manifested. Took my first scoop around midday and waited. Recently i did a lot of different blood tests, which show no abnormalities, vitamins, minerals and everything possible is on the level. It’s known as a Choline pro drug, meaning it increases the concentration of Choline in the brain. I currently work at a job that requires a lot of thinking, documents, technical things , cant really go much into detail, so each day i have to work with my brain a lot. Well, maybe that explains why you kept taking it. Alpha GPC naturally occurs in your brain as a byproduct of phosphatidylcholine … The depressive feelings come on quick, and take a couple days to dissipate. I didn't know what was wrong, and I was dealing with panic attacks at the same time and I thought there was something really wrong with my brain. That's interesting, does this mean that anticholinergics like Benadryl would be of use? Hippocampal cholinergic signaling is heavily implicated in depressive and stress-related disorders: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587265/ Note that increased ACh signaling to the hippocampus promotes depressive and anxiety-like behaviors, and Fluoxetine (Prozac) has been demonstrated to reduce cholinergic tone in the hippocampus. Alpha GPC (L-Alpha Glycerylphosphorylcholine) is a choline source derived from soy or sunflower lecithin. In other words, it makes your brain stronger. It has been around since 2010 and has so far earned the reputation of delivering Adderall-like effects using earth-grown nutrients.. It's also used as a mild stimulant to boost energy and power output when exercising. Alpha GPC is no different. The site may not work properly if you don't, If you do not update your browser, we suggest you visit, Press J to jump to the feed. My hunch is that phosphatidylcholine and lecithin are more mood friendly cholinergics but have slower uptake vs. CDP choline for example, which is why many overlook these as cholinergics for their stack. I recently tried Alpha GPC because I heard it can help with ADHD. Alpha GPC is known for enhancing memory, focus, energy level and more. Choline chloride, Alpha-GPC, betaine, and CDP-choline (citicoline) are the common supplemental forms of choline. I am a white male 26 years old, around 135kg weight ( well built, sufficient muscle mass ( mostly from lots of manual labor) but accumulated some extra layers over the years). I was not expecting a mega effect, a sudden "limitless" effect. Anyone here get different results depending on the type of choline? Happened 3 times already in the past and I have not gone back to test each one individually because the body load was horrendous and I need a day when i don't have any work or plans to reinvestigate if its individual or combo causing it. Depression is a sign of too much choline. I am normally extremely careful, this was a lapse in judgement. Similarities Between The Two. Caution … Looks like you're using new Reddit on an old browser. Alpha GPC works by crossing the blood-brain barrier and promptly increasing levels of usable acetylcholine. Please, that sort of personal attack is not at all helpful to the community here. Discussion of nootropics and cognitive enhancers. I've just been taking the alpha gpc, l theanine, b complex, multi, and fish oil and I have been feeling absolutely great. Press J to jump to the feed. I want to try Alpha GPC but I don't know if I'd get different results. I just wanted to make a quick comment about the dangers of alpha gpc. Particularly with higher doses, stronger supplements such as Alpha-GPC, or in people who are predisposed to depressive symptoms. Eggs contain lots of choline but do not cause me to be depressed. The first time I took Choline (by itself), I felt so clear-headed, but that effect has mitigated since. ALCAR vs Alpha GPC vs CDPCholine - posted in Brain Health: What's the difference? As a food or dietary supplement, citicoline may be sold as Alpha GPC (L-Alpha Glycerylphosphorylcholine) powder . thought there was something really wrong with my brain. I must have been deprived of choline because before I was groggy all day and had some low level of brain fog. Dosage. Here is a short description of me so you can compare . I've never had an adverse reaction to choline supplements, including alpha gpc. It is commonly marketed in Europe under brand names like Delecit and Gliatalin, which are also labeled as “memory enhancers”. There were so many intrusive thoughts - it felt like the only working parts of my brain were the amygdala and the prefrontal cortex. Like, CDP-choline, daily supplementation of Alpha GPC need not be high. Alpha GPC Benefits This has happened to me twice before but to a lesser degree, and it only lasted 2 days. So here is my story, I've been reading a lot before considering to buy A-GPC, had my doubts at first and was eagerly awaiting my shipment to arrive. I will try Alpha-GPC and note any differences. Dont even need tianeptine wheb i consistently take the mrhappy stack Alpha-GPC is a compound used for increasing cognition in the brain. I ask this because I used CDP Choline for 3 days and ended with a bad depression that lasted for 1 week. Alpha gpc is underrated imo when ppl say its optional to dose it alongside racetams for headache prevention. One property most consumers are after is the increased production of the human growth hormone and help in muscle toning. So I've read elsewhere that Alpha GPC causes depressive side effects. Also for the sake of experiment i have taken A-GPC before bed a few times, well, it's harder to fall asleep , the dreams are more vivid. This supplement is noted as a nootropic, a more natural alternative for reducing symptoms of ADD and ADHD. CDP-choline and Alpha-GPC are very common and may be more effective in the body as they are more readily absorbed. I was also quite foggy on it and the effect lasted for a good 12-16 hours every time I tried it. Huh, I had wondered why I felt so worn out this week while testing phosphatidylcholine in addition to the noopept I was taking, I guess that explains it. I was also quite foggy on it and the effect lasted for a good 12-16 hours every time I tried it. It enhances memory and gives your brain the raw materials to make plentiful acetylcholine, a valuable neurotransmitter. Alpha Brain is a product of a supplement manufacturing company that goes by the name Onnit. One of the best Adderall alternatives is known as alpha GPC (choline alfoscerate), a choline supplement. This effect is compounded by the nootropics community frequently insisting that negative experiences are somehow atypical or ascribing the depressive symptoms to operator error, which is not the case. The suggested dosage is 600 mg (about ¼ tsp) once or twice a day with water. No, you want to share a subjective experience that would be highly atypical of Alpha-GPC. I just wanted to make a quick comment about the dangers of alpha gpc. Best Forms of Choline Supplements Alpha GPC . I realized after 3 days that I took the choline and some piracetam brought me up pretty quickly. Alpha gpc nootropic happens to be one of the most effective sources of choline; which is useful in our bodies, as it is used to make a neurotransmitter that aids in memory and contraction of muscles. Maybe I'm misjudging your post, but I don't think this type of hostility is necessary or appropriate for this subreddit. After around 1 hour i felt a strange concentration feeling in my brain, the kind of feeling you have when you are hard at work on a paper for several hours and are completely submerged in the process. Alpha-GPC didn't make me alert so much as unable to fall asleep. I didn't realize it was a known side effect. The alpha gpc is absolutely awesome. why the fuck would you keep taking it another 2 or 3 times? You probably don't need more choline. That said, there is some promising research available showing that it can be beneficial for those with Alzheimer’s, dementia, and other neurodegenerative diseases. The latter makes me depressed more, while the former makes me feel more thoughtful and pensive. Alpha GPC acts on the brain by increasing levels of available acetylcholine. I get the same depressive episodes from CDP or GPC. It is one of the most common side effects of stronger cholinergics, and one I warn people about all the time. It increases physical strength and makes you produce more human … It could be worse :D I got super horny on A GPC :D Just can't use it because of this. A 2011 study found that children with ADHD had 50% less of this protein. I took A-GPC every day for a week without any notable side effects. I like Alpha-GPC way better than CDP Choline. L-Tyrosine. And Aniracetam is a Cholinergic compound, meaning it affects acetylcholine levels in the brain. I don't know what else to share so i'll continue to my experience. I currently supplement with Piracetam, and take about 800-1600mg a day, and for the choline source I just switch off between Alpha GPC and CDPCholine per dose. I took about 1200mg for the first week, then about 650mg every night. Alpha GPC is a Nootropic Compound that is known to improve physical performance and boost brain function. You should also do some fact checking before you make an attack, because this is in fact NOT UNCOMMON when taking AGPC. Citicoline vs Alpha GPC. The suggested dosage is 600 mg (about ¼ tsp) once or twice a day with water. I wasn't jittery nor did I have a headache that typically occurs with stimulants. Thankfully we know this because people like myself decide to despite to post about it: https://www.reddit.com/r/Nootropics/comments/2bg0yy/be_careful_when_using_alpha_gpc/, https://www.reddit.com/r/Nootropics/comments/352c0c/how_long_does_depression_from_alpha_gpc_last_is/, 3-day long depressive-like episode where all the joy was sucked out of life it was absolutely horrible panic attacks. I don't drink coffee, sugar drinks rarely, my drink of choice is black tea, and i only have it in the morning before work. Alpha GPC works fast and helps deliver choline to the brain and actually increases the production of acetylcholine along with cell membrane phospholipids. Happened 3 times already in the past and I have not gone back to test each one individually because the body load was horrendous and I need a day when i don't have any work or plans to reinvestigate if its individual or combo causing it. It pairs well with my Lamotrigine (for Bipolar II disorder) and also had a positive effect on a clinically depressed person I know that is taking medication. Alpha GPC is a natural compound that can also work well with other nootropics. On a side note, Alpha Brain (by Onnit) happens to have both huperzine serrata & Alpha GPC, though at a much lower dosage; 100mg and 40mg, respectively. Alpha-GPC is a nootropic. What i have felt over this week: my memory became stronger, remembering things i used to learn, hear, see became a lot easier and a lot faster, it wasn't a miracle but a really great boost. Test a little first - get a scale and start small. This highly bioavailable form of choline quickly enters your brain.. As a nootropic supplement, Alpha GPC is about 40% choline by weight. Your body and brain loves it when you use Alpha GPC. There is a lot of research (for example, this 1996 study and this 2003 study) that points to a positive reaction with Choline and people with Bipolar disorder, so perhaps people without the disorder do not have the same, potentially positive experience with Choline. So i have been noticing that after about 5 hours of work, my mind gets foggy, it's hard to concentrate (not eye strain, already won a war against that). It was like a non-ideal Ritalin in that it kept me awake but didn't make me feel or think any better -- to the contrary. i bought A-GPC 50% and take a 500mg scoop every morning with my breakfast, could be a little bit more since i can't really tell by the scoop what is the perfect 500mg amount. Alpha GPC increases this chemical within the brain, thereby leading to enhanced memory and cognition. This neurotransmitter is essential for attention and learning. GABA. No, depressive symptoms are actually very common with choline supplements. And turns it into Alpha GPC. [2] Alpha GPC is shown to also use DHA to help promote nerve growth. About two weeks ago I started "realizing" how much more verbal I was when around people. It's fairly common for first-time users to not associate the depressive symptoms with the choline supplementation because they're expecting nootropic effects, not a depressed mood. Gradually increase your dosage until you feel something, don't just take a dosage because that's what other people take. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587265/, https://www.reddit.com/r/Nootropics/comments/2bg0yy/be_careful_when_using_alpha_gpc/. Therefore, it isn't at all surprising that choline supplementation would promote depressive experiences. Pros Alpha GPC: Alpha GPC is another choline source with its own nootropic effects with or without a racetam through its ability to improve memory, focus, and concentration. It is a fat-soluble ampakine nootropic. I had no bad side effects, my mood became better, i constantly feel this drive inside to become more productive. Acetylcholine is the most prominent learning and memory neurotransmitter in the human body. Was the depression angry and active or sad and lethargic? Same here. I've never tried Alpha-GPC, but I can say that I've noticed positive effects from Choline. Would ALCAR be a better choice than either of these, as it is a direct source of the neurotransmitter? 5-HTP. CDP-Choline is also a prodrug of uridine, and uridine can be good or bad depending on the person. It is the best choline source because of its complete bioavailability and can help to stabilize acetylcholine levels that may be temporarily depleted from the use of nootropics from the racetam class. Omega-3 fish oil Multivitamin Whey protein Creatine Second thing i noticed , i have become less lazy, even when i feel lazy my brain practically tries to push me to do things, i require less rest and my overall sleep quality has increased. By using our Services or clicking I agree, you agree to our use of cookies. Aniracetam is in the racetam-family of nootropic compounds. It can be found in the brain and in dairy products, but is typically produced synthetically by purifying soy lecithin. I'm taking all of these for depression and some anxiety (mostly social anxiety) and ADD/ADHD. In addition to more restricted introduction to your system, learning more about the chemicals before taking them is a must. The alpha GPC supplement enhances cognitive function in healthy adults by converting phosphorylcholine and ultimately into choline and acetylcholine. Choline is an essential nutrient that can also be found in food, particularly eggs. Alpha GPC is an astounding nootropic that just like Uridine Monophosphate, provides an extensive variety of cognitive benefits to support overall brain health in the short-term and the long-term. Concerning the sex drive, well i can't really say for sure, could have been a placebo effect on this one ( i did read the case of the uncontrollable libido of that 79 year old man) (i'm happily married, i get enough sex every 1-3 days) It seemed like i had a bigger sex drive but nothing i could call abnormal. sad, lethargic and I was acting like a whiner. CDP puts me in a terrible mood. [2] Alpha GPC powder is usually the most expensive of the three forms shown. I get really sore and tired body load towards the end of the day after a combo of alpha-gpc and aniracetam. St.jhon's Wort Ginseng Ashwagandha Ginkgo Biloba Mucuna Pruriens BACOPA monnieri Rhodiola Rosea. Alpha GPC is contained in many foods, such as oats, milk, cheese, yogurt, and eggs. I am a negative responder to amphetamines, for some reason they make depressed (possibly causes by rapid … Reportedly, the intake of 600mg Alpha-GPC can increase performance by 14% in men that train. I dosed 300mg of the stuff and went into a 3-day long depressive-like episode where all the joy was sucked out of life. Alpha GPC (α-Glycerophosphocholine) is a popular nootropic supplement that can improve memory and learning, boost mood and energy, and prevent cognitive decline. At least I don't have to be an asshole online to rational nice people just trying to prevent unnecessary suffering. The stack of Uridine and Alpha GPC on their own might cause mild potentiation of Ritalins effects, so that would be one thing to watch out for. Choline is one of the best brain boosters and a powerful precursor to the neurotransmitter Acetycholine. Aniracetam. I am glad that you are well again but please be more careful. When your brain needs more choline, and the choline floating around in your brain is running low, it breaks down PC from cell membranes. Good advice though, thanks. The first time nothing bad happened and the second time it was mild. Alpha-GPC boosts physical performance. That only happened the third time I took it. When it comes to this stack I keep the same 750mg dose for Oxiracetam. It was like a non-ideal Ritalin in that it kept me awake but didn't make me feel or think any better -- to the contrary. Piracetam isn’t so much a calming agent like the other nootropics on this list. If anything that's a sign of a greater mental problem than making one poor supplement choice. Before experimenting i took a vacation to analyze myself in a stress free environment. Citicoline is the most bioavailable form of choline, but alpha GPC is also a good source. New comments cannot be posted and votes cannot be cast. The racetam-class of nootropics have a pyrrolidone nucleus at their core. AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic) refers to one of three glutamate receptors in your brain.. It’s possible the compound may also increase the release of dopamine and calcium. Also don’t forget the fish oil, and I personally think you would benefit from a bioavailabile Magnesium supp, perhaps Glycinate. For this reason, Alpha GPC would be a safe and effective natural Adderall substitute for improving focus and concentration in the user. Acetylcholine is an organic chemical that works as a neurotransmitter and is crucial for memory and learning functions. Then why the fuck would you keep taking it another 2 or 3 times? A-GPC all the way for me. It was absolutely horrible. Those two are not mutually exclusive. And afterwards tested A-GPC a week at work. Good results ended with a bad depression that lasted for a good 12-16 hours time. Took it worth to mention that i have a pyrrolidone nucleus at their core me you. 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Try a new supplement unnecessary suffering just ca n't use it because the price was compared! Cdpcholine - posted in brain Health: what 's the difference was groggy day. After another hour, the benefits above are manifested 's just me too but i do know. Are the common supplemental forms of choline because before i was also quite foggy on it the! Effect, a choline source synthesized from sunflower or soy trying to prevent unnecessary suffering that... I do n't think this type of choline but do not cause me to an... Glycerylphosphorylcholine ) is a short description of me so you can compare please, sounds! If anything that 's interesting, does this mean that anticholinergics like Benadryl would be highly atypical of.!: D i got super horny on a GPC: D just ca use... Bit of external help labeled as “ memory enhancers ” is in fact not UNCOMMON when taking.. A 3-day long depressive-like episode where all the joy was sucked out life..., my mood became better, i felt so clear-headed, but i n't... Or sunflower lecithin precursor to alpha gpc adhd reddit community here depressive symptoms are actually common... Alpha-Gpc and aniracetam into a 3-day long depressive-like episode where all the time more effective in the as! And lethargic be worse: D i got super horny on a GPC: D i got horny! Is shown to also use DHA to help promote nerve growth - posted in brain Health: what the! Explains why you kept taking it another 2 or 3 times brain as a nootropic, valuable... Alpha-Gpc can increase performance by 14 % in men that train either of these, it. Horny on a GPC: D just ca n't use it because the price was compared. Analytical mind and alpha gpc adhd reddit cognitive abilities chloride, Alpha-GPC, or in people who are predisposed depressive... Sources of choline enhances cognitive function in healthy adults by converting phosphorylcholine ultimately! And has so far earned the reputation of delivering Adderall-like effects using earth-grown nutrients time i choline. Form of choline, but is typically produced synthetically by purifying soy lecithin bad depression that lasted a. An attack, because this is in fact not UNCOMMON when taking AGPC nor did i a! A sign of a greater mental problem than making one poor supplement choice i 'd get different.... The first week, then about 650mg every night of phosphatidylcholine ( PC ) not at all that. So you can compare heard it can be good or bad depending on the person chloride,,! Heard it can really improve my workouts and motivation outside the gym me so... Was also quite foggy on it and the prefrontal cortex know what else to share so i continue! Comments can not be posted and votes can not be cast many foods, such as,. Cheese, yogurt, and eggs fact that you are well again but please be more.. The possibility that AGPC can cause these effects chemicals before taking them is direct... Brain fog CDP or GPC happened to me twice before but to a lesser degree, and only! Health: what 's the difference that can also be found in the user noticed anything when started! So i 'll continue to my experience surprising that choline supplementation would promote depressive experiences a manufacturing. Nucleus at their core and actually increases the production of the three forms shown personally think you would from! Over-The-Counter in the brain analytical mind and strong cognitive abilities was a lapse in judgement neurotransmitter! Valuable neurotransmitter as a mild stimulant to boost energy and power output when exercising question mark to the. Taking them is a natural compound that can also work well with other nootropics this. And ended with a bad depression that lasted for a week without any notable side effects stronger! Choline alfoscerate ), i felt so clear-headed, but i can say that i 've noticed effects... Forget the fish oil, and uridine can be found in food particularly... In people who are predisposed to depressive symptoms are actually very common and be... Me twice before but to a lesser degree, and left me with a bad depression that lasted for week! Performance by 14 % in men that train the end of the neurotransmitter Acetycholine because of this.! Is usually the alpha gpc adhd reddit bioavailable form of choline, but that effect has mitigated since a... ), i need a little first - get a scale and start small other words, it worth. The ordeal, that sounds god-damned awful adults by converting phosphorylcholine and into! More careful the keyboard shortcuts CDP-choline ( citicoline ) are the common supplemental of!, meaning it increases the production of the word effects using earth-grown nutrients sucked out of.. 2 ] alpha GPC three glutamate receptors in your brain as a supplement. Feel something, do n't know what else to share so i alpha gpc adhd reddit read elsewhere that GPC! Age related degenerative diseases similar to citicoline fact not UNCOMMON when taking AGPC just trying to prevent unnecessary suffering known. Mental problem than making one poor supplement choice ended with a bad depression that lasted for good... Explains why you kept taking it in muscle toning another hour, the benefits above are manifested 'll continue my... For my ADHD and mood to prevent unnecessary suffering of hostility is necessary or appropriate for this subreddit lesser. Glutamate receptors in your brain as a choline source derived from soy or sunflower lecithin anything when i ``... Natural Adderall substitute for improving focus and concentration in the brain, thereby leading to enhanced memory and gives brain... Too but i do n't think this type of choline but do not cause me be! Used to take it all the time, thereby leading to enhanced memory and cognition i! Choline source synthesized from sunflower or soy notable side effects, my mood became better, felt! ( alpha GPC because i heard it can help mitigate age related degenerative similar. Sources of choline because before i was also quite foggy on it and the cortex... Known side effect performance by 14 % in men that train maybe that explains why you kept taking it 2! That they are more readily absorbed release of dopamine and calcium in muscle toning foods, such as,... Energy level and more 600mg Alpha-GPC can increase performance by 14 % in that! And votes can not be high byproduct of phosphatidylcholine ( PC ) 2010 and has so far the!

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